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This from CNN:

U.S. citizens Mario R. Capecchi and Oliver Smithies and Sir Martin J. Evans of Britain won the 2007 Nobel Prize in medicine on Monday for groundbreaking discoveries that led to a technique for manipulating mouse genes.

The widely used process has helped scientists use mice to study heart disease, diabetes, cancer, cystic fibrosis and other diseases.

Capecchi, 70, who was born in Italy, is at the University of Utah in Salt Lake City. Smithies, 82, born in Britain, is at the University of North Carolina in Chapel Hill. Evans, 66, works at Cardiff University in Wales.

They were honored for a technique called gene targeting, which lets scientists inactivate or modify particular genes in mice. That in turn lets them study how those genes affect health and disease.